"I refuse to stop poking the leopards' anuses," Nyanzi wrote in the post that has received over 4,000 reactions and 500 shares.
"I am going to continue poke-poking all the leopards' anuses until either Uganda is free from the leopards or my death. This fugitive is not shutting up!"
On Tuesday Nyanzi wrote again on Facebook, comparing the government to parasitic pubic lice that "are sucking me dry!"
Freeing Nyanzi on bail last week after a month in custody, the judge refused a prosecution request that the academic be blocked from "making any adverse cyber attacks or any derogatory statements against the person of the victim (President Museveni) or his close members of his household."
Nyanzi's posts have attracted both scorn and applause in Uganda, a traditionally conservative country but one where many are fed up with Museveni's long rule.
Nyanzi is due in court again on 25 May.